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Genetic research on Parkinson’s Disease
Sporadic Parkinson’s disease (PD) is thought to result
from a complex interaction between multiple predisposing genes
and environmental influences. Professor
Halliday and her colleagues are hoping to determine how
the genes controlling inflammation may be involved. Finding
any other genes influencing Parkinson’s disease may
illuminate the etiologic process and molecular mechanisms.
With permission, DNA samples will be extracted either from
brain tissue or from blood cells and molecular DNA typing
performed.
How can I help this research? By
participating in our
DNA donation and
brain donor programs (contact 02 9036 7117). Blood will
also be prepared for immortalisation of lymphocytes.
Key researchers
Glenda Halliday, Yue Huang Greg Sutherland, Naomi Cook and
Julia Stevens
Collaborators
Dominic Rowe (University of Sydney, Royal North Shore
Hospital)
Key publications
Huang Y, Cheung L, Rowe DB, Halliday GM (2004) Genetic
contributions to Parkinson's disease, Brain Research Reviews,
46:44-70
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