The research group was established in 2001, with research labs based at POWMRI, linked to the Prince of Wales Clinical School UNSW and the Institute of Neurological Sciences, Prince of Wales Hospital. The group works in close collaboration with Professor David Burke at the University of Sydney (combined ARC Discovery grant) and Professor Hugh Bostock FRS at the Institute of Neurology, Queen Square, London UK (combined fellowships and program grant collaborations). This 15-strong team of clinicians, scientists, biomedical engineers and research students has a multi-focussed approach to neurological disease. Current projects are directed to:
We are also conducting clinical trials aimed at neuroprotective and physical therapies in neurological diseases. Our research is intrinsically linked to the provision of local clinical services, particularly the multidisciplinary motor neurone disease clinic; the hereditary nerve and muscle clinics run through Prince of Wales Hospitals; neurological consultation and clinical neurophysiological investigations.
Effects of marine neurotoxins on impulse transmission (tetrodotoxin; ciguatera)Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Establishment of training programs for health care professionals to look after MND Patients (Australian Government Dept of Health and Ageing grant).Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Mechanisms of chemotherapy induced neurotoxicity (NHMRC Project Grant)Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Mechanisms of neurodegeneration in motor neurone disease (NHMRC Project Grant)Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Nerve excitability in spinal cord injury patients (NSW Ministry for Science and MedicalMatthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Nocturnal hypoventilation in motor neurone diseaseMatthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Pathophysiology of uraemic neuropathyMatthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Patterns of neuronal degeneration in motor neurone disease (NSW Ministry for Science and Medical ResearchMatthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Research Spinal Cord Injury & Related Neurological Conditions Research Program Grant).Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
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Role of inherited mutations of neuronal Na+ channels in epileptic patientsMatthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Site of origin of motor neurone disease (MND Research Institute of Australia)Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
Spinal Cord Injury & Related Neurological Conditions Research Project Grant).Matthew Kiernan's research has delineated disease mechanisms that involve neuronal ion channels, and has identified targets for potential therapies in patients with neurological disease. |
The Australian Motor Neurone Disease RegistryThe Australian Motor Neurone Disease Registry, launched by Matthew Kiernan on MND global awareness day, June 21st, 2005, at the Annual conference for Health and Community Care Providers. |
